Cancer as a Metabolic Disease

1st Edition · By Thomas N. Seyfried

Cancer as a Metabolic Disease: On the Origin, Management, and Prevention of Cancer challenges the dominant genetic mutation theory of cancer and presents compelling evidence that cancer is fundamentally a metabolic disorder driven by mitochondrial dysfunction.

Drawing on decades of biochemical, genetic, and clinical research, Dr. Thomas N. Seyfried reframes cancer as a disease of impaired energy metabolism rather than defective genes. The book explains how cancer cells depend on fermentation for survival and how this vulnerability can be targeted through metabolic therapies.

What This Book Covers

This text integrates historical research, experimental evidence, and clinical insight into a unified metabolic theory of cancer. It explores the Warburg effect, mitochondrial dysfunction, and the biochemical foundations of metabolic-based cancer management.

Key Features

• Revolutionary perspective redefining cancer as a metabolic disease
• Strong scientific foundation supported by experimental and clinical data
• In-depth discussion of mitochondrial dysfunction and energy metabolism
• Exploration of ketogenic diets and calorie restriction as therapies
• Clear links between glucose metabolism, fermentation, and tumor growth
• Clinical relevance for oncology, nutrition, and integrative medicine

Table of Contents Highlights

• The Metabolic Theory of Cancer
• The Warburg Effect and Energy Metabolism
• Mitochondrial Dysfunction in Tumorigenesis
• Experimental Evidence for Metabolic Origin
• Metabolic Management Strategies
• Ketogenic Diet and Caloric Restriction
• Future Directions in Metabolic Oncology

A transformative scientific work redefining how cancer is understood and treated.
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