- Type: Hardcover Book
- Publisher: Swedish Pharmaceutical Press
- Language : English
Pharmacokinetic and Pharmacodynamic Data Analysis: Concepts and Applications, 5th Edition (ISBN 9789198299106)
Pharmacokinetic and Pharmacodynamic Data Analysis (PK/PD), 5th Edition by Johan Gabrielsson and Daniel Weiner is a comprehensive, practice-focused reference for analyzing drug concentration–time and effect–time data. Blending conceptual clarity with hands-on techniques, the book walks readers from fundamental PK/PD principles to advanced modeling, simulation, and decision-making in drug development.
Product Details
- Title: Pharmacokinetic and Pharmacodynamic Data Analysis: Concepts and Applications
- Edition: 5th Edition
- Authors: Johan Gabrielsson, Daniel Weiner
- ISBN-13: 9789198299106
- Price: $169.99
- Availability: In Stock | Free Shipping on all orders
What This Book Does
This text provides end-to-end guidance for extracting reliable information from PK/PD data and translating it into dosing strategies and development decisions. It covers study design, data handling, model selection, parameter estimation, and interpretation—linking theory to real-world workflows in academia and industry.
Key Features of the 5th Edition
- Foundations to Advanced: Core PK/PD concepts through population modeling, covariate analysis, and simulation-based decision support.
- Compartmental & NCA: Clear explanations of compartmental and noncompartmental analysis, including assumptions and limitations.
- PK/PD Link Models: Direct, indirect, effect-compartment, and turnover models with practical guidance for selection and fitting.
- Model Diagnostics: Residual analysis, goodness-of-fit checks, visual predictive checks (VPCs), and predictive performance.
- Design & Simulation: Dose/regimen optimization, power and precision, and scenario testing to inform development decisions.
- Hands-On Orientation: Examples and workflows compatible with common tools used in PK/PD analysis.
Table of Contents Highlights
- PK/PD Study Design and Data Structures
- Noncompartmental Analysis (NCA) and Exposure Metrics
- Compartmental Models: Absorption, Distribution, Elimination
- PD Models: Direct, Indirect, Effect-Compartment, Turnover
- Population Approaches and Covariate Modeling
- Parameter Estimation, Variability, and Uncertainty
- Model Qualification: GOF, Residuals, VPCs, Predictive Checks
- Simulation for Dose Selection and Trial Design
- Case Studies and Decision Frameworks
Who Should Use This Book?
- Pharmacometricians and clinical pharmacologists
- Biostatisticians and modelers in drug development
- Regulatory and medical affairs professionals needing PK/PD fluency
- Graduate students and researchers in pharmaceutical sciences
Why Choose BooksGoat?
- Best Price: $169.99
- Free Shipping: On all orders
- Reliable Sourcing: Professional packaging and prompt dispatch
- Support: Responsive customer care for institutions and labs
FAQs
- Is this suitable for beginners in PK/PD?
- Yes. It starts with foundations and progresses to advanced population modeling and simulation.
- Does it cover model diagnostics and qualification?
- Yes. Residuals, GOF, VPCs, and predictive performance are treated in depth to support robust decisions.
- Will this help with dose/regimen optimization?
- Yes. Simulation-driven strategies for dosing and trial design are a core focus.
Final Call – Buy Now
Pharmacokinetic and Pharmacodynamic Data Analysis, 5th Edition is a definitive resource for PK/PD practitioners. Order now from BooksGoat for just $169.99. Free shipping on all orders.
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